SB-431542

• Target :

  Apoptosis|||ALK|||TGF-beta/Smad

• Related Pathways :

  Stem Cells|||Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors

• Purity :

  >99.99%

• Bioactivity :

  SB-431542 is an inhibitor of ALK5/TGF-? type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells.

• Smiles :

  NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCOc2c1

• Molecular Formula :

  C22H16N4O3

• Molecular Weight :

  384.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  301836-41-9