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SB-431542

CAT: 0931-T1726-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T1726-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
301836-41-9
Target
Apoptosis, ALK, TGF-beta/Smad
Related Pathways
Stem Cells, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells.
Smiles
NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCOc2c1
Molecular Formula
C22H16N4O3
Molecular Weight
384.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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