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Tonabersat

CAT: 0931-T17116-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T17116-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
175013-84-0
Target
Gap Junction Protein
Related Pathways
Cytoskeletal Signaling
Purity
0.9949
Bioactivity
Tonabersat (SB-220453) is a novel and orally available gap-junction modulator and CSD (Cortical spreading depression) inhibitor that regulates cellular communication between trigeminal ganglion neuronal cells and glial cells and inhibits neurogenic inflammation for the treatment of migraine and epilepsy.
Smiles
N(C(=O)C1=CC(Cl)=C(F)C=C1)[C@H]2C=3C(OC(C)(C)[C@H]2O)=CC=C(C(C)=O)C3
Molecular Formula
C20H19ClFNO4
Molecular Weight
391.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C