TCS 2314

• Target :

  Integrin

• Related Pathways :

  Cytoskeletal Signaling

• Bioactivity :

  TCS 2314 (compound 3) is a potent and selective VLA-4 (?4?1 integrin; CD49d/CD29) antagonist with an IC50 of 4.4 nM. It exhibits high plasma clearance and low oral bioavailability in rats, making it suitable for asthma research.

• Smiles :

  C(=O)([C@H]1N(C(CC2=CC=C(NC(NC3=C(C)C=CC=C3)=O)C=C2)=O)CCOC1)N4CCC(CC(O)=O)CC4

• Molecular Formula :

  C28H34N4O6

• Molecular Weight :

  522.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  317353-73-4