TC-I 2014

• Target :

  TRP/TRPV Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  0.9907

• Bioactivity :

  TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectively) .

• Smiles :

  FC(F)(F)c1ccccc1-c1cc(c2[nH]c(nc2c1)C1=NOC2(C1)CCCCC2)C(F)(F)F

• Molecular Formula :

  C23H19F6N3O

• Molecular Weight :

  467.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1221349-53-6