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TC-I 2014

CAT: 0931-T17006-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T17006-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1221349-53-6
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9907
Bioactivity
TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectively) .
Smiles
FC(F)(F)c1ccccc1-c1cc(c2[nH]c(nc2c1)C1=NOC2(C1)CCCCC2)C(F)(F)F
Molecular Formula
C23H19F6N3O
Molecular Weight
467.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C