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Donafenib

CAT: 0931-T16909-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16909-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1130115-44-4
Target
FLT, Ferroptosis, VEGFR, Apoptosis, Autophagy, Raf
Related Pathways
MAPK, Angiogenesis, Autophagy, Tyrosine Kinase/Adaptors, Apoptosis
Purity
0.9988
Bioactivity
Donafenib (Bay 43-9006 (D3) ) is a deuterium-labeled Sorafenib which is a multikinase inhibitor (IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively) .
Smiles
[2H]C([2H])([2H])NC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Molecular Formula
C21H13ClD3F3N4O3
Molecular Weight
467.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BUP05292-01Donafenib
C14368-25mgDonafenib (Sorafenib D3)
A21489-100Donafenib (Sorafenib D3) 100mg
A21489-10Donafenib (Sorafenib D3) 10mg
A21489-50Donafenib (Sorafenib D3) 50mg
A21489-25Donafenib (Sorafenib D3) 25mg
A21489-5Donafenib (Sorafenib D3) 5mg
A21489-1Donafenib (Sorafenib D3) 1mg
A21489-10mM-DDonafenib (Sorafenib D3) 10mM * 1mL in DMSO

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