SB-267268

• Target:

  Others|||Integrin

• Related Pathways:

  Cytoskeletal Signaling|||Others

• Bioactivity:

  SB-267268 inhibits human and mouse ?v?3 (IC50s: 0.68 and 0.29 nM, respectively) . SB-267268 is a selective and nonpeptidic alpha (v) beta3 and alpha (v) beta5 integrins antagonist (Kis: 0.9, 0.5 and 0.7 nM for human ?v?3, monkey ?v?3 and human ?v?5, respectively) .

• Smiles:

  C(C(F)(F)F)N1CC=2C(C[C@@H](CC(O)=O)C1=O)=CC=C(OCCCNC3=CC=CC=N3)C2

• Molecular Formula:

  C22H24F3N3O4

• Molecular Weight:

  451.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  205678-26-8