Rebeccamycin

• Target:

  ADC Cytotoxin|||Antibiotic|||Topoisomerase

• Related Pathways:

  Microbiology/Virology|||DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.

• Smiles:

  O=C1C2=C3C(N(C=4C3=CC=CC4Cl)[C@@]5(O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)[H])=C6C(=C2C(=O)N1)C=7C(N6)=C(Cl)C=CC7

• Molecular Formula:

  C27H21Cl2N3O7

• Molecular Weight:

  570.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  93908-02-2