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Puromycin aminonucleoside

CAT: 0931-T16684-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T16684-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
58-60-6
Target
Apoptosis, Proteasome, Antibiotic, Antibacterial, Aminopeptidase
Related Pathways
Apoptosis, Proteases/Proteasome, Ubiquitination, Metabolism, Microbiology/Virology
Purity
0.9997
Bioactivity
Puromycin aminonucleoside (NSC 3056) is an aminonucleoside antibiotic and a purine analog of puromycin. It can reversibly inhibit dipeptidyl peptidase and cytosolic alanine aminopeptidase, increase podocyte permeability by regulating ZO-1 in an oxidative stress-dependent manner, induce apoptosis, and promote the secretion of migrasomes. It is commonly used to induce nephrotic syndrome models in research.
Smiles
CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1O
Molecular Formula
C12H18N6O3
Molecular Weight
294.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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