Fludrocortisone

CAT: 0931-T1666L-02Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No

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CAT#:0931-T1666L-02Size:1 mL - 10 mM (in DMSO)

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

127-31-1

Target

Others, Sodium Channel, Glucocorticoid Receptor

Related Pathways

Membrane transporter/Ion channel, Endocrinology/Hormones, Others

Purity

0.9866

Bioactivity

Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and greater mineralocorticoid potency. Fludrocortisone is in research use for the treatment of hypotension.[3]

Smiles

C[C@]12C[C@H](O)C3(F)[C@@H](CCC4=CC(=O)CC[C@]34C)C1CCC2(O)C(=O)CO

Molecular Formula

C21H29FO5

Molecular Weight

380.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Fludrocortisone

Fludrocortisone is a mineralocorticoid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(4) steroid, a fluorinated steroid and a C21-steroid. It has a role as an anti-inflammatory drug and an adrenergic agent. It derives from a hydride of a pregnane.

CAS Number	127-31-1
PubChem CID	31378
IUPAC Name	(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Molecular Formula	C21H29FO5
Molecular Weight	380.4
XLogP	1.7
Topological Polar Surface Area	94.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Heavy Atom Count	27
Formal Charge	0
Complexity	734

SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)F

InChI

InChI=1S/C21H29FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-16,23,25,27H,3-8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1

InChIKey

AAXVEMMRQDVLJB-BULBTXNYSA-N

Chemical Structure

2D Structure

CAS: 127-31-1

CID: 31378

Formula: C21H29FO5

MW: 380.4

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	380.4
XLogP3	1.7
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	380.19990218
Monoisotopic Mass	380.19990218
Topological Polar Surface Area	94.8 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	734
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BA7985-5	Fludrocortisone
FF23322-01	Fludrocortisone acetate

Fludrocortisone

Chemical Information

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