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PKF050-638

CAT: 0931-T16548-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16548-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
528893-52-9
Target
HIV Protease, CRM1
Related Pathways
Proteases/Proteasome, Microbiology/Virology, Membrane transporter/Ion channel
Bioactivity
PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC50=0.04 μM) .
Smiles
C(=C\C(OCC)=O)\N1C(=NC=N1)C2=C(N)C=CC(Cl)=C2
Molecular Formula
C13H13ClN4O2
Molecular Weight
292.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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