PKF050-638

• Target:

  HIV Protease|||CRM1

• Related Pathways:

  Proteases/Proteasome|||Microbiology/Virology|||Membrane transporter/Ion channel

• Bioactivity:

  PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC50=0.04 ?M) .

• Smiles:

  C(=C\C(OCC)=O)\N1C(=NC=N1)C2=C(N)C=CC(Cl)=C2

• Molecular Formula:

  C13H13ClN4O2

• Molecular Weight:

  292.72

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  528893-52-9