Mardepodect

CAT: 0931-MF-0033769-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0033769-01Size:1 mg
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CAS Number
898562-94-2
Target
PDE
Related Pathways
Metabolism
Purity
0.9994
Bioactivity
Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM and over 1000-fold selectivity over PDE. It is potentially useful for the treatment of schizophrenia. Phosphodiesterase 10A (PDE10A) is highly expressed in striatal medium spiny neurons of both the direct and indirect output pathways. Mardepodect can cross the blood-brain barrier.
Smiles
Cn1cc(c(n1)-c1ccc(OCc2ccc3ccccc3n2)cc1)-c1ccncc1
Molecular Formula
C25H20N4O
Molecular Weight
392.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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