PF-06263276

• Target:

  Others|||STAT|||JAK

• Related Pathways:

  Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Others|||Stem Cells

• Bioactivity:

  PF-06263276 is an effective and selective inhibitor of pan-JAK. It also has IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.

• Smiles:

  CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1cnc(cn1)N1CCCCC1

• Molecular Formula:

  C31H31FN8O2

• Molecular Weight:

  566.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1421502-62-6