PF-04991532

• Target:

  Glucokinase

• Related Pathways:

  Metabolism

• Purity:

  0.9999

• Bioactivity:

  PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model, with human and rat EC50 values of 80 and 100 nM respectively.

• Smiles:

  [C@H](CC1CCCC1)(C(NC2=CC=C(C(O)=O)C=N2)=O)N3C=C(C(F)(F)F)N=C3

• Molecular Formula:

  C18H19F3N4O3

• Molecular Weight:

  396.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1215197-37-7