PBIT

• Target:

  Histone Demethylase|||Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9995

• Bioactivity:

  PBIT inhibits JARID1B histone demethylase (IC50 of about 3 ?M) . PBIT also inhibits JARID1A and JARID1C (IC50s of 6 ?M and 4.9 ?M, respectively) . PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .

• Smiles:

  CC1=CC=C (C=C1) N1SC2=CC=CC=C2C1=O

• Molecular Formula:

  C14H11NOS

• Molecular Weight:

  241.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2514-30-9