Pregnenolone acetate

Pregnenolone acetate

• CAS Number: 1778-02-5
• UNSPSC Description: Pregnenolone acetate (compound #43), a nonmetabolized Pregnenolone (HY-B0151) analog, can promote neurite extension and induce a change in growth cone morphology in primary cultures of cerebellar granule neurons. Pregnenolone acetate, a neurosteroid, increases microtubule polymerization. Pregnenolone acetate has the potential for neurodevelopmental diseases research[1].
• Target Antigen: Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/pregnenolone-acetate.html
• Purity: 98.40
• Smiles: C[C@@]12[C@](CC[C@@H]2C(C)=O)([H])[C@@]3([H])[C@]([C@@]4(C(C[C@H](CC4)OC(C)=O)=CC3)C)([H])CC1
• Molecular Weight: 358.51
• References & Citations: [1]Viktoryia Kolas, et al. A synthetic pregnenolone analog promotes microtubule dynamics and neural development. Cell Biosci. 2022 Dec 1;12(1):190.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported