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Nitroaspirin

CAT: 0931-T16328-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16328-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
175033-36-0
Target
COX, Apoptosis
Related Pathways
Immunology/Inflammation, Apoptosis, Neuroscience
Purity
0.9932
Bioactivity
Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin that inhibits cyclooxygenase. It induces cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells by down-regulating EGFR/PI3K/STAT3 signaling and modulating Bcl-2 family proteins. Additionally, Nitroaspirin possesses antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
Smiles
O(C(C)=O)C1=C(C(OC2=CC(CON(=O)=O)=CC=C2)=O)C=CC=C1
Molecular Formula
C16H13NO7
Molecular Weight
331.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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BUP12832-01Nitroaspirin
A19145-5Nitroaspirin 5mg
A19145-200Nitroaspirin 200mg
A19145-100Nitroaspirin 100mg
A19145-25Nitroaspirin 25mg
A19145-10Nitroaspirin 10mg
A19145-50Nitroaspirin 50mg
A19145-1Nitroaspirin 1mg
A19145-10mM-DNitroaspirin 10mM * 1mL in DMSO

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