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MRT00033659

CAT: 0931-T16141-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T16141-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1401731-54-1
Target
Others, MDM-2/p53, Chk, Early 2 Factor (E2F), Casein Kinase
Related Pathways
Metabolism, Cell Cycle/Checkpoint, Apoptosis, Stem Cells, Others
Bioactivity
MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 μM for CK1δ) and CHK1 (IC50=0.23 μM) . MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.
Smiles
CC(=O)Nc1cccc(c1)-c1cnc2[nH]nc(C)c2c1
Molecular Formula
C15H14N4O
Molecular Weight
266.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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