ML753286

• Target :

  BCRP|||AMPK

• Related Pathways :

  PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Membrane transporter/Ion channel

• Bioactivity :

  ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 ?M) . It is also stable in plasma across species.

• Smiles :

  [H][C@]12Cc3c([nH]c4cc(OC)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](C)NC2=O

• Molecular Formula :

  C20H25N3O3

• Molecular Weight :

  355.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1699720-89-2