ML753286

• Target:

  BCRP|||AMPK

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Membrane transporter/Ion channel

• Bioactivity:

  ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 ?M) . It is also stable in plasma across species.

• Smiles:

  [H][C@]12Cc3c ([nH]c4cc (OC) ccc34) [C@H] (CC (C) C) N1C (=O) [C@H] (C) NC2=O

• Molecular Formula:

  C20H25N3O3

• Molecular Weight:

  355.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1699720-89-2