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LY 345899

CAT: 0931-T15827-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15827-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
10538-99-5
Target
DHFR, Dehydrogenase
Related Pathways
Metabolism, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.997
Bioactivity
LY 345899 is a folate analog that inhibits methylenetetrahydrofolate dehydrogenase and MTHFD2, with IC50 values of 96 nM and 663 nM, respectively, and a Ki of 18 nM for MTHFD1.
Smiles
Nc1nc2NCC3CN(C(=O)N3c2c(=O)[nH]1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Molecular Formula
C20H21N7O7
Molecular Weight
471.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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GTR19156922-01LY 345899
A19440-25LY 345899 25mg
A19440-10LY 345899 10mg
A19440-1LY 345899 1mg
A19440-500LY 345899 500mg
A19440-100LY 345899 100mg
A19440-50LY 345899 50mg
A19440-5LY 345899 5mg
A19440-10mM-DLY 345899 10mM * 1mL in DMSO

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