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Lexibulin dihydrochloride

CAT: 0931-T15746-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T15746-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
917111-49-0
Target
Apoptosis, Reactive Oxygen Species, Others, ROS, Microtubule Associated
Related Pathways
Apoptosis, Metabolism, Immunology/Inflammation, Others, NF-κB, Cytoskeletal Signaling
Bioactivity
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines) . It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
Smiles
COC1=C(NC(NCC)=O)C=CC(C2=NC=C(C)C(N[C@H](C3=CN=CC=C3)CCC)=N2)=C1.Cl.Cl
Molecular Formula
C24H32Cl2N6O2
Molecular Weight
507.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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