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Lexibulin

CAT: 0931-T2090-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T2090-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
917111-44-5
Target
ROS, Microtubule Associated, Reactive Oxygen Species, Apoptosis
Related Pathways
Metabolism, Cytoskeletal Signaling, NF-κB, Immunology/Inflammation, Apoptosis
Purity
0.9922
Bioactivity
Lexibulin (CYT-997) (CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines) . Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this may result in disruption of the tumor vasculature and tumor blood flow, and tumor cell death.
Smiles
CCC[C@H](Nc1nc(ncc1C)-c1ccc(NC(=O)NCC)c(OC)c1)c1cccnc1
Molecular Formula
C24H30N6O2
Molecular Weight
434.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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