ITX3

CAT: 0931-T15602-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T15602-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
347323-96-0
Target
ROCK|||Rho|||Others
Related Pathways
Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Stem Cells|||Others
Purity
0.9902
Bioactivity
ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 ?M. ITX3 has anticancer effects, inhibits trion mediated GTP exchange on RhoG and Rac1, inhibits NGF-mediated neurite growth in PC12 cells and REF52 fibroblast structure formation induced by trion.
Smiles
Cc1cc(\C=c2\sc3nc4ccccc4n3c2=O)c(C)n1-c1ccccc1
Molecular Formula
C22H17N3OS
Molecular Weight
371.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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