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ITX3

CAT: 0013-GTR19203744-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203744-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ITX3 is a potent and selective inhibitor of the TrioN RhoGEF domain, exhibiting an IC50 of 76 μM. It effectively blocks Trio-mediated activation of RhoG and Rac1 GTPases, which underlies its utility in studying cell morphology, neurite outgrowth in PC12 cells, and fibroblast structural changes in vitro.
CAS Number
347323-96-0
Product Name Alternative
ITX 3, ITX3, ITX-3, Rho GEFs
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.28% (May vary between batches)
Solubility
DMSO:4 mg/mL (10.77 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1cc (\C=c2\sc3nc4ccccc4n3c2=O) c (C) n1-c1ccccc1
Molecular Formula
C22H17N3OS
Molecular Weight
371.45
Storage Conditions
-20°C
Notes
For research use only.

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