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Indibulin

CAT: 0931-T15576-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T15576-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
204205-90-3
Target
Microtubule Associated, Apoptosis, Chk
Related Pathways
Apoptosis, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Purity
0.9983
Bioactivity
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis.
Smiles
Clc1ccc(Cn2cc(C(=O)C(=O)Nc3ccncc3)c3ccccc23)cc1
Molecular Formula
C22H16ClN3O2
Molecular Weight
389.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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