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Hematein

CAT: 0931-T15469-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T15469-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
475-25-2
Target
Wnt/beta-catenin, Apoptosis, Akt, Casein Kinase
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Metabolism, Apoptosis, Stem Cells
Bioactivity
Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway, and increases apoptosis in lung cancer cells. Hematein is an oxidation product of hematoxylin acted as a dye and it also is an allosteric casein kinase II inhibitor (IC50: 0.74 μM) .
Smiles
OC1=CC2=C3c4ccc(O)c(O)c4OCC3(O)CC2=CC1=O
Molecular Formula
C16H12O6
Molecular Weight
300.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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