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Helenalin

CAT: 0931-T15467Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15467Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
6754-13-8
Target
NF-κB, Others
Related Pathways
Others, NF-κB
Bioactivity
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-κB, helenalin effectively inhibits its DNA binding.
Smiles
[H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](O)[C@]1([H])C(=C)C(=O)O2
Molecular Formula
C15H18O4
Molecular Weight
262.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C