Helenalin

• Target:

  NF-?B|||Others

• Related Pathways:

  Others|||NF-?B

• Bioactivity:

  Helenalin is a selective inhibitor of transcription factor NF-?B by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-?B, helenalin effectively inhibits its DNA binding.

• Smiles:

  [H][C@@]12C[C@@H] (C) [C@]3 ([H]) C=CC (=O) [C@@]3 (C) [C@@H] (O) [C@]1 ([H]) C (=C) C (=O) O2

• Molecular Formula:

  C15H18O4

• Molecular Weight:

  262.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  6754-13-8