GPNA hydrochloride

• Target:

  Apoptosis|||ASCT

• Related Pathways:

  Apoptosis|||Membrane transporter/Ion channel

• Purity:

  0.9991

• Bioactivity:

  GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2 (SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme ?-glutamyltransferase (GGT) . GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2.

• Smiles:

  Cl.NC(=O)CCC(Nc1ccc(cc1)[N+]([O-])=O)C(O)=O

• Molecular Formula:

  C11H14ClN3O5

• Molecular Weight:

  303.7

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  67953-08-6