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GPNA hydrochloride

CAT: 0931-T15411-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T15411-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
67953-08-6
Target
Apoptosis, ASCT
Related Pathways
Apoptosis, Membrane transporter/Ion channel
Purity
0.9991
Bioactivity
GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2 (SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT) . GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2.
Smiles
Cl.NC(=O)CCC(Nc1ccc(cc1)[N+]([O-])=O)C(O)=O
Molecular Formula
C11H14ClN3O5
Molecular Weight
303.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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