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GN44028

CAT: 0931-T15396-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15396-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1421448-26-1
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Metabolism, Angiogenesis, Chromatin/Epigenetic
Purity
0.9952
Bioactivity
GN44028 (N- (2,3-Dihydro-1,4-benzodioxin-6-yl) -1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF) -1 (IC50: 14 nM) . GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. However, It can not be suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization.
Smiles
C1c2ccccc2-c2[nH]nc(Nc3ccc4OCCOc4c3)c12
Molecular Formula
C18H15N3O2
Molecular Weight
305.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
E7505-1mgGN44028
A19693-200GN44028 200mg
A19693-1GN44028 1mg
A19693-10GN44028 10mg
A19693-5GN44028 5mg
A19693-100GN44028 100mg
A19693-50GN44028 50mg
A19693-25GN44028 25mg
A19693-10mM-DGN44028 10mM * 1mL in DMSO
bs-60325C-01GN44028 --- HIF-1α Inhibitor

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