Rapamycin

• Target:

  Endogenous Metabolite|||Antifungal|||Autophagy|||mTOR|||FKBP|||Antibacterial|||Antibiotic

• Related Pathways:

  Autophagy|||Immunology/Inflammation|||Microbiology/Virology|||Metabolism|||Apoptosis|||PI3K/Akt/mTOR signaling

• Purity:

  0.998

• Bioactivity:

  Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM) . Rapamycin has immunosuppressive activity and induces autophagy.

• Smiles:

  [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC

• Molecular Formula:

  C51H79NO13

• Molecular Weight:

  914.17

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  53123-88-9