G-744

• Target :

  BTK

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity :

  G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM) . G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.

• Smiles :

  O=C1C2=C(C3=C(S2)CC(C)(C)C3)CCN1C4=C(CO)C(=CC=C4)C=5C=C(NC=6C=CN=CN6)C(=O)N(C)C5

• Molecular Formula :

  C29H29N5O3S

• Molecular Weight :

  527.64

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1346669-54-2