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Flindokalner

CAT: 0931-T15286-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15286-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
187523-35-9
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9996
Bioactivity
Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. It is also a positive modulator of large conductance calcium-activated K channels (BKca) and displays negative modulatory activity at Kv7.1 channels (Ki = 3.7 μM) . Additionally, Flindokalner acts as a negative modulator of GABAA receptors and demonstrates anxiolytic efficacy in vivo.
Smiles
COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F
Molecular Formula
C16H10ClF4NO2
Molecular Weight
359.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
525063Flindokalner
HY-108584R-01Flindokalner (Standard)

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