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Fenobam

CAT: 0931-T15275-07Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T15275-07Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
57653-26-6
Target
Apoptosis, GluR
Related Pathways
Neuroscience, Apoptosis
Purity
0.9993
Bioactivity
Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity (IC50: 84 nM) . Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively) .
Smiles
CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1
Molecular Formula
C11H11ClN4O2
Molecular Weight
266.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Fenobam Anhydrous

Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X Syndrome).

CAS Number57653-26-6
PubChem CID135497698
IUPAC Name1-(3-chlorophenyl)-3-(1-methyl-4-oxoimidazolidin-2-ylidene)urea
Molecular FormulaC11H11ClN4O2
Molecular Weight266.68
XLogP1.2
Topological Polar Surface Area73.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity385
SMILES
CN1CC(=O)NC1=NC(=O)NC2=CC(=CC=C2)Cl
InChI
InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)
InChIKey
DWPQODZAOSWNHB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Fenobam Anhydrous
CAS: 57653-26-6
CID: 135497698
Formula: C11H11ClN4O2
MW: 266.68
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight266.68
XLogP31.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass266.0570533
Monoisotopic Mass266.0570533
Topological Polar Surface Area73.8 Ų
Heavy Atom Count18
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count1
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B7035-50Fenobam
NCA54028-01Fenobam (hydrate)
MBS5811514Fenobam hydrate
A20372-200Fenobam 200mg
A20372-25Fenobam 25mg
A20372-10Fenobam 10mg
HY-101478RFenobam (Standard)
A20372-100Fenobam 100mg
A20372-50Fenobam 50mg
A20372-5Fenobam 5mg

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