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Eact

CAT: 0931-T15192-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15192-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
461000-66-8
Target
Chloride channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9862
Bioactivity
Eact is a selective and potent TMEM16A activator that directly activates the TRPV1 channels in sensory nociceptors, thereby producing itch, acute nociception, and thermal hypersensitivity (brackets) .
Smiles
COCCN(C(=O)c1cc(OC)c(OC)c(OC)c1)c1nc(cs1)-c1ccccc1
Molecular Formula
C22H24N2O5S
Molecular Weight
428.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS Number461000-66-8
PubChem CID3173542
IUPAC Name3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
Molecular FormulaC22H24N2O5S
Molecular Weight428.5
XLogP3.7
Topological Polar Surface Area98.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Heavy Atom Count30
Formal Charge0
Complexity520
SMILES
COCCN(C1=NC(=CS1)C2=CC=CC=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC
InChI
InChI=1S/C22H24N2O5S/c1-26-11-10-24(22-23-17(14-30-22)15-8-6-5-7-9-15)21(25)16-12-18(27-2)20(29-4)19(13-16)28-3/h5-9,12-14H,10-11H2,1-4H3
InChIKey
ZUXNHFFVQWADJL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
CAS: 461000-66-8
CID: 3173542
Formula: C22H24N2O5S
MW: 428.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight428.5
XLogP33.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass428.14059304
Monoisotopic Mass428.14059304
Topological Polar Surface Area98.4 Ų
Heavy Atom Count30
Formal Charge0
Complexity520
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T11142-01EACC

Alternative Products

CatalogName
448043-01Eact
A16179-5Eact 5mg
A16179-1Eact 1mg
A16179-2Eact 2mg
A16179-100Eact 100mg
A16179-25Eact 25mg
A16179-10Eact 10mg
A16179-50Eact 50mg
A16179-10mM-DEact 10mM * 1mL in DMSO
217839TMEM16A Activator, Eact (3,4,5-trimethoxy-N- (2-methoxyethyl) -N- (4-phenylthiazol-2-yl) benzamide, ANO1 Activator)

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