E 2012

CAT:

931-T15184-01

Size:

50 mg

Price:

Ask

CAS Number :
870843-42-8
Target :
Gamma-secretase
Related Pathways :
Stem Cells|||Proteases/Proteasome|||Neuroscience
Purity :
0.9983
Bioactivity :
E2012 is a ?-secretase modulator (GSM) . E2012 inhibits 3?-hydroxysterol ?24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid ?-42, and induces cataract following repeated doses in the rat.
Smiles :
COc1cc(\C=C2/CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1
Molecular Formula :
C25H26FN3O2
Molecular Weight :
419.49
Shipping Conditions :
Cool pack
Storage Temperature :
-20°C

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