E 2012

CAT: 0931-T15184-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T15184-01Size:50 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

870843-42-8

Target

Gamma-secretase

Related Pathways

Stem Cells, Proteases/Proteasome, Neuroscience

Purity

0.9983

Bioactivity

E2012 is a γ-secretase modulator (GSM) . E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.

Smiles

COc1cc(\C=C2/CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1

Molecular Formula

C25H26FN3O2

Molecular Weight

419.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-10016-01	E 2012
MBS3606322-01	E-2012
A11393-100	E 2012 100mg
A11393-10	E 2012 10mg
A11393-5	E 2012 5mg
A11393-2	E 2012 2mg
A11393-1	E 2012 1mg
HY-10016R	E 2012 (Standard)
A11393-25	E 2012 25mg
A11393-50	E 2012 50mg

E 2012

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