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DNA2 inhibitor C5

CAT: 0931-T15146-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15146-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
35973-25-2
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9905
Bioactivity
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM) . DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
Smiles
OC(=O)c1cnc2c(cccc2c1O)[N+]([O-])=O
Molecular Formula
C10H6N2O5
Molecular Weight
234.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C