Calyculin A

• Target :

  Phosphatase

• Related Pathways :

  Metabolism

• Purity :

  0.98

• Bioactivity :

  Calyculin A ((-) -Calyculin A), a toxicant in the Japanese marine sponge CDiscodermia calyxC, is a selective and potent inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), inducing hyperactivation of cryopreserved bovine spermatozoa and inhibiting radiation-induced gammaH2AX DNA repair disease in human lymphocytes. gammaH2AX DNA repair foci in human lymphocytes.

• Smiles :

  C[C@@]1(C)[C@@]2(O[C@]([C@H](C[C@@H]([C@@H]([C@@H]([C@@H](/C=C(/C(=C/C=C/C(=C\C#N)/C)/C)\C)C)O)C)O)OC)([C@@H]1OP(=O)(O)O)[H])O[C@@H](C/C=C/C=3N=C([C@H](CCNC([C@H]([C@H]([C@H](COC)N(C)C)O)O)=O)C)OC3)[C@@H](C)[C@H](O)C2

• Molecular Formula :

  C50H81N4O15P

• Molecular Weight :

  1009.17

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  101932-71-2