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Methotrexate

CAT: 0931-T1485-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T1485-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
59-05-2
Target
ADC Cytotoxin, Dehydrogenase, Apoptosis, DNA/RNA Synthesis, Antifolate
Related Pathways
Antibody-drug Conjugate/ADC Related, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Metabolism, Apoptosis
Purity
0.9991
Bioactivity
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
Smiles
NC=1C2=C(N=CC(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)N=C(N)N1
Molecular Formula
C20H22N8O5
Molecular Weight
454.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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