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BT2

CAT: 0931-T14834-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T14834-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
34576-94-8
Target
Bcl-2 Family
Related Pathways
Apoptosis
Purity
0.9986
Bioactivity
BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, leading to BDK's dissociation from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) .
Smiles
OC(=O)c1sc2cc(Cl)ccc2c1Cl
Molecular Formula
C9H4Cl2O2S
Molecular Weight
247.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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