BRD9185

CAT: 0931-T14780Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T14780Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2057420-29-6

Target

DNA/RNA Synthesis, Parasite, Dehydrogenase

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Metabolism, Microbiology/Virology

Bioactivity

BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.

Smiles

C(#N)[C@@H]1[C@@H]([C@@H](CO)N1C(NCCC)=O)C2=CC=C(C=C2)C3=CC(C(F)(F)F)=C(C(F)(F)F)C=C3

Molecular Formula

C23H21F6N3O2

Molecular Weight

485.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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