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Begacestat

CAT: 0931-T14525Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T14525Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
769169-27-9
Target
Gamma-secretase, Beta Amyloid
Related Pathways
Proteases/Proteasome, Stem Cells, Neuroscience
Bioactivity
Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor (γ-secretase) that inhibits Amyloid-beta production with nanomolar potency, selectively inhibits cleavage of APP in cellular level Notch cleavage assays, reverses situational memory deficits, and can be used to study Alzheimer's disease.
Smiles
C([C@H](NS(=O)(=O)C=1SC(Cl)=CC1)CO)(C(F)(F)F)C(F)(F)F
Molecular Formula
C9H8ClF6NO3S2
Molecular Weight
391.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A11258-100Begacestat (GSI-953) 100mg
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