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AZ1495

CAT: 0931-T14367-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14367-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2196204-23-4
Target
IRAK, CDK, Haspin Kinase
Related Pathways
Cell Cycle/Checkpoint, NF-κB, Immunology/Inflammation
Purity
0.9881
Bioactivity
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL) .
Smiles
C1CC(CCO1)c1c[nH]c2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c12
Molecular Formula
C21H31N5O2
Molecular Weight
385.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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