Trifluridine

• Target:

  Autophagy|||Nucleoside Antimetabolite/Analog|||Apoptosis|||HSV|||DNA/RNA Synthesis|||Virus Protease

• Related Pathways:

  Apoptosis|||Autophagy|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Microbiology/Virology

• Purity:

  0.9982

• Bioactivity:

  Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.

• Smiles:

  O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(F)(F)F)C(=O)N1

• Molecular Formula:

  C10H11F3N2O5

• Molecular Weight:

  296.2

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  70-00-8