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AM679

CAT: 0931-T14205Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14205Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1206880-66-1
Target
Cytochromes P450, LTR, FLAP
Related Pathways
Metabolism, Immunology/Inflammation
Purity
0.9945
Bioactivity
AM679 is a potent and selective FLAP inhibitor with IC50 values of 2.2 nM (FLAP binding), 0.6 nM (hLA), and 154 nM (hWB) . AM679 displays improved CYP inhibition characteristics, no CYP3A4 time-dependent inhibition or induction, and strong in vivo leukotriene inhibition in rodent BAL models after oral administration.
Smiles
C(N1C=2C(C(SC(C)(C)C)=C1CC(C(O)=O)(C)C)=CC(OC[C@H]3N(C(C)=O)C=4C(C3)=CC=CC4)=CC2)C5=CC=C(C=C5)C=6N=CC(OC)=CN6
Molecular Formula
C40H44N4O5S
Molecular Weight
692.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
A3169-25AM679
A14994-100AM679 100mg
A14994-50AM679 50mg
A14994-10AM679 10mg
A14994-25AM679 25mg
A14994-5AM679 5mg

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