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Gemfibrozil

CAT: 0931-T1415-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T1415-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
25812-30-0
Target
PPAR, Cytochromes P450, Adrenergic Receptor
Related Pathways
GPCR/G Protein, Metabolism, DNA Damage/DNA Repair, Neuroscience
Purity
0.999
Bioactivity
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfibrozil is a fibric acid derivative with hypolipidemic effects. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III) . The reduction in hepatic production of apoC-III result in the subsequent reduction of serum levels of very-low-density-lipoprotein cholesterol (VLDL-C) . In addition, gemfibrozil-mediated PPARalpha stimulation of apoA-I and apoA-II expression results in an increase in high-density lipoprotein cholesterol (HDL-C) .
Smiles
CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
Molecular Formula
C15H22O3
Molecular Weight
250.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
FD23652-01Gemfibrozil
278313-01Iso-Gemfibrozil (gemfibrozil impurity)

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