TL13-12

• Target:

  PROTACs|||ALK

• Related Pathways:

  PROTAC|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  TL13-12 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.69 nM) .

• Smiles:

  COc1cc (ccc1Nc1ncc (Cl) c (Nc2ccccc2S (=O) (=O) C (C) C) n1) N1CCN (CCOCCOCCNC (=O) CNc2cccc3C (=O) N (C4CCC (=O) NC4=O) C (=O) c23) CC1

• Molecular Formula:

  C45H53ClN10O10S

• Molecular Weight:

  961.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2229037-04-9