TL13-12

• Target:

  PROTACs|||ALK

• Related Pathways:

  PROTAC|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  TL13-12 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.69 nM) .

• Smiles:

  COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCN(CCOCCOCCNC(=O)CNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1

• Molecular Formula:

  C45H53ClN10O10S

• Molecular Weight:

  961.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2229037-04-9