THS-044

• Target:

  HIF/HIF Prolyl-Hydroxylase|||HIF

• Related Pathways:

  Metabolism|||Angiogenesis|||Chromatin/Epigenetic

• Purity:

  >99.99%

• Bioactivity:

  THS-044 (N-[2-Nitro-4- (Trifluoromethyl) phenyl]morpholin-4-Amine) binding stabilizes the HIF2? PAS-B folded state with a kd of 2 ?M and regulates HIF2 activity in endogenous and clinical settings.

• Smiles:

  [O-][N+](=O)c1cc(ccc1NN1CCOCC1)C(F)(F)F

• Molecular Formula:

  C11H12F3N3O3

• Molecular Weight:

  291.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  62054-67-5