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MAK683-CH2CH2COOH

CAT: 0931-T13765-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T13765-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2639882-68-9
Target
Histone Methyltransferase, Ligands for Target Protein for PROTAC, Others
Related Pathways
Chromatin/Epigenetic, Others, PROTAC
Bioactivity
MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein) and, together with a VHL ligand for the E3 ubiquitin ligase, has been used to design EED-Targeted PROTACs, specifically EED degrader-1 and PROTAC EED degrader-2 [1].
Smiles
N(CC1=C2C(OCC2)=CC=C1F)C=3N4C(C(=CN3)C5=C(C)N=C(CCC(O)=O)C=C5)=NN=C4
Molecular Formula
C23H21FN6O3
Molecular Weight
448.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-130815MAK683-CH2CH2COOH
MBS5815982MAK683-CH2CH2COOH hydrochloride
HY-130815A-01MAK683-CH2CH2COOH (hydrochloride)
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HY-103663AMAK683 (hydrochloride)
HO016016-2K-01CH2CH2COOH-PEG-CH2CH2COOH, 2K
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