MAK683-CH2CH2COOH

• Target :

  Histone Methyltransferase|||Ligands for Target Protein for PROTAC|||Others

• Related Pathways :

  Chromatin/Epigenetic|||Others|||PROTAC

• Bioactivity :

  MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein) and, together with a VHL ligand for the E3 ubiquitin ligase, has been used to design EED-Targeted PROTACs, specifically EED degrader-1 and PROTAC EED degrader-2 [1].

• Smiles :

  N(CC1=C2C(OCC2)=CC=C1F)C=3N4C(C(=CN3)C5=C(C)N=C(CCC(O)=O)C=C5)=NN=C4

• Molecular Formula :

  C23H21FN6O3

• Molecular Weight :

  448.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2639882-68-9