Lycopodine

CAT: 0931-T13764-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T13764-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
466-61-5
Target
Caspase|||Apoptosis|||Lipoxygenase
Related Pathways
Apoptosis|||Metabolism|||Proteases/Proteasome
Bioactivity
Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity.
Smiles
O=C1[C@@]2([C@]34[C@@]([C@](C1)(C[C@@H](C)C3)[H])(CCC[N@]4CCC2)[H])[H]
Molecular Formula
C16H25NO
Molecular Weight
247.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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