CP-10

CAT: 0931-T13627-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T13627-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2366268-80-4

Target

PROTACs, CDK

Related Pathways

PROTAC, Cell Cycle/Checkpoint

Bioactivity

CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1 nM) . It inhibits the proliferation of several hematopoietic cancer cells including multiple myeloma and can degrade mutated and overexpressed CDK6.

Smiles

O=C1C=2C=CC=C(NCCOCCN3N=NC(=C3)CN4CCN(C5=CN=C(C=C5)NC=6N=CC7=C(N6)N(C(=O)C(C(=O)C)=C7C)C8CCCC8)CC4)C2C(=O)N1C9C(=O)NC(=O)CC9

Molecular Formula

C44H49N13O7

Molecular Weight

871.94

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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CP-10

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