CP-10

• Target:

  PROTACs|||CDK

• Related Pathways:

  PROTAC|||Cell Cycle/Checkpoint

• Bioactivity:

  CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1 nM) . It inhibits the proliferation of several hematopoietic cancer cells including multiple myeloma and can degrade mutated and overexpressed CDK6.

• Smiles:

  O=C1C=2C=CC=C(NCCOCCN3N=NC(=C3)CN4CCN(C5=CN=C(C=C5)NC=6N=CC7=C(N6)N(C(=O)C(C(=O)C)=C7C)C8CCCC8)CC4)C2C(=O)N1C9C(=O)NC(=O)CC9

• Molecular Formula:

  C44H49N13O7

• Molecular Weight:

  871.94

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2366268-80-4