PF-06733804

• Target :

  Trk receptor

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.

• Smiles :

  O([C@H]1CN(C(CC2=CC=C(OC(F)(F)F)C=C2)=O)CC1(F)F)C=3C=C(C(NC)=O)C=NC3N

• Molecular Formula :

  C20H19F5N4O4

• Molecular Weight :

  474.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1873373-33-1